Thrombocytopenia during pregnancy: An Institutional based study

Rajshree Dayanand Katke, Dhruv Pravin Gohil.

Abstract:

Background: Thrombocytopenia affects 6% to 10% of all pregnant women and other than anemia is the most common hematologic disorder in pregnancy. All pregnant women with platelet counts less than 100000/mm3 require careful hematological and obstetric consultation to exclude more serious disorders. Objectives of the study were to study the number and percentage of cases, the various etiological factors associated, the effect and outcome of the mother and neonates borne.

Methods: The study was conducted in this tertiary institute over a period of two years and three months. 103 pregnant patients with a platelet count of or less than 100000/mL were included. The course of pregnancy was studied and the investigation profile was monitored.

Results: Out of 103 cases of thrombocytopenia, 73 (70.9%) patients had moderate, 30 (29.1%) patients had severe thrombocytopenia. In this study 35% cases were primigravidas, 32% cases were gravida 2, 33% cases were gravida 3 to 5. Gestational thrombocytopenia was the most common etiological factor with 30.1% cases, 27.2% cases due to hypertensive disorders, 18.4% cases due to malaria followed by 12.6% cases due to dengue. In the study group the mean gestational age was 33 ± 5.139, maximum cases belonged to gestational age 30 to ≥40. 14 patients (14.1%) had still births. 9 patients (8.7%) had Neonatal deaths (NNDs).

Conclusions: The challenge to the clinician is to weigh the risks of maternal and fetal bleeding complications against the benefits of diagnostic tests and interventions.

Key words: Thrombocytopenia, Pregnancy

For Full Article Link:

http://www.scopemed.org/fulltextpdf.php?mno=167914